Molecular markers in gastrointestinal cancer: targeted therapy and tailored chemotherapy.
نویسنده
چکیده
منابع مشابه
Systemic Targeted Alpha Radiotherapy for Cancer
Background: The fundamental principles of internal targeted alpha therapy for cancer were established many decades ago.The high linear energy transfer (LET) of alpha radiation to the targeted cancer cellscauses double strand breaks in DNA. At the same time, the short range radiation spares adjacent normal tissues. This targeted approach complements conventional external beam radiotherapy and ch...
متن کاملThree cycles of AC chemotherapy regimen increased oxidative stress in breast cancer patients: A clinical hint
Background: Recent studies have suggested the importance of oxidant/antioxidant status in initiation and progression of breast cancer. The aim of this study was to evaluate oxidative stress markers in breast cancer patients before and after 3 cycles of chemotherapy with adriamycin and cytoxan (AC). Also, in this study the effect of age and the stage of disease on oxidative stress markers were c...
متن کاملSafe chemotherapy and targeted therapy for treating locally advanced NPC in a G6PD-deficient patient: case report and literature review
The article was first report a case of a 32-year-old female with NPC that is G6PD-deficient. The patient completed induction chemotherapy and concomitant chemoradiotherapy successfully. The patient experienced grade 1 neutropenia , grade 1 diarrhea, and grade 2 acne-like skin reactions during the three cycles of induction chemotherapy. Grade 1 neutropenia, grade 1 diarrhea, grade 2 oral mucosi...
متن کاملProgress in Rectal Cancer Treatment
The dramatic improvement in local control of rectal cancer observed during the last decades is to be attributed to attention to surgical technique and to the introduction of neoadjuvant therapy regimens. Nevertheless, systemic relapse remains frequent and is currently insufficiently addressed. Intensification of neoadjuvant therapy by incorporating chemotherapy with or without targeted agents b...
متن کاملProduction and Evaluation of Specific Single-Chain Antibodies against CTLA-4 for Cancer-Targeted Therapy
Background: Cytotoxic T lymphocyte–associated antigen 4 (CTLA-4) molecules are expressed on T-cells and inhibit their function by inhibiting activation of subsequent T-cell molecular pathways. Blocking of CTLA-4 inhibits the growth of malignant tumor cells. Anti-CTLA-4 monoclonal antibodies activate the immune system against cancer. Due to several advantages of single-chain antibodi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Onkologie
دوره 27 1 شماره
صفحات -
تاریخ انتشار 2004